Product Name :
TSC2/Tuberin Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
FLJ43106 antibody LAM antibody OTTHUMP00000158940 antibody OTTHUMP00000198394 antibody OTTHUMP00000198395 antibody PPP1R160 antibody Protein phosphatase 1, regulatory subunit 160 antibody tsc2 antibody TSC2_HUMAN antibody TSC4 antibody 展开
Function :
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas.2313230-37-2 custom synthesis Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin.N-Boc-O-tosyl hydroxylamine uses Tuberin and hamartin interact with each other forming a cystoplasmic complex.PMID:33389413 Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within Human TSC2 aa 1,758-1,807 / 1,807.
Species reactivity:
Human, Mouse
Verify application:
IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3073328
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Positive control :
SH-SY-5Y, PANC-1, human liver tissue, mouse brain tissue, human pancreas tissue, mouse pancreas tissue, mouse liver tissue.