Product Name :
Thioredoxin Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
ADF antibody ATL-derived factor antibody SASP antibody Surface associated sulphydryl protein antibody TRN antibody TXN 1 antibody TXN antibody
Function :
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within Human Thioredoxin aa 66-105 / 105.
Species reactivity:
Human, Mouse
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3073360
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.1259509-27-7 Price 4), 0.1092365-58-6 Chemscene 2% BSA, 40% Glycerol.PMID:33723488 Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
12 kDa, additional band 40 kDa
Positive control :
Hela, HepG2, A431, PC-3M, MCF-7, human liver tissue, human kidney tissue, mouse kidney tissue.