Product Name :
SCF Mouse Monoclonal Antibody [4G5]
Predicted band size :
Observed band size :
Synonyms:
C kit ligand antibody C-kit ligand antibody Ckit ligand antibody DCUA antibody DFNA69 antibody DKFZp686F2250 antibody familial progressive hyperpigmentation 2 antibody FPH2 antibody FPHH antibody KIT ligand antibody 展开
Function :
Stem cell factor (SCF) is the ligand for the transmembrane tyrosine kinase receptor proto-oncogene c-Kit. SCF, also designated KL, MGF and SLF, is a pleiotropic cytokine that has two alternatively spliced forms, 248 and 220 amino acids in length in human and mouse systems, respectively.Formula of 4-(Methoxycarbonyl)nicotinic acid Both the larger form and the smaller form are cleaved to produce soluble forms. The smaller splice variant lacks the proteolytic cleavage site, between amino acids 149 and 177 of the larger SCF form. The larger SCF form is expressed in fibroblasts, brain and thymus, while the smaller SCF form is found in the spleen, testis, placenta and cerebellum. The SCF ligand is essential for the development of germ cells, hematopoietic progenitor cells and melanocyte precursors. With respect to mast cells, SCF can stimulate the proliferation of mature mast cells as well as the maturation and proliferation of immature mast cells
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Amino acids 26-214 of SCF of human origin.N-Fmoc-N-(2-phenylethyl)-glycine supplier
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IP, IF, IHC-P
Coupling :
unconjugated
Clone number:
4G5
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃
Storage buffer solution:
1.PMID:33558170 0 ml of PBS with
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
48kDa
Positive control :
MCF7, COLO320DM, rat brain tissue, mouse brain tissue, human colon tissue, human lung tissue, human small intestine tissue